PL EN
LETTER TO EDITORS
Autism – environmental risk
 
More details
Hide details
1
Instytut Medycyny Pracy i Zdrowia Środowiskowego. Kierownik: mgr K. Kuźniewski
 
2
Katedra i Zakład Higieny Uniwersytetu Medycznego we Wrocławiu. Kierownik: prof. dr hab. n. med. K. Pawlas
 
 
Corresponding author
Henryka Langauer-Lewowicka   

Instytut Medycyny Pracy i Zdrowia Środowiskowego ul. Kościelna 13, 41-200 Sosnowiec tel. 32 634 12 00
 
 
Med Srod. 2016;19(2):19-23
 
KEYWORDS
ABSTRACT
The incidence of infantile autism due to developmental brain disorders has been permanently increasing in many parts of the world. Autism is characterized by impairments of communication and reciprocal social interaction and by restricted repetitive behaviours or interests. The causes of these disorders are not yet known. Experimental studies and clinical observation suggest that genetic and environmental factors could converge to result in neurotoxic mechanisms. These may lead to the development of autistic spectrum disorders (ASD). Several recent studies have indicated that perinatal exposure to environmental toxins may be the risk factor for ASD, among them: polybrominated diphenyl, esters, phthalates, bisphenol A, tetrabrombisphenol A, solvents, pesticides, and heavy metals. They can easily pass the placental and blood brain barriers and affect brain development.
REFERENCES (32)
1.
Kanner L.: Autistic disturbances of affective contact. Nerv Child 1943; 2: 217-250.
 
2.
Golaska P.: Etiologia zaburzeń ze spektrum autyzmu. Przegląd wybranych koncepcji. Psychiatr Psychol Klin 2013; 13(1): 8-14.
 
3.
Rybakowski F.: Współczesne rozumienie zaburzeń ze spektrum autyzmu – epidemiologia, obraz kliniczny i badania genetyczne. Wiad Psychiatr 2012; 15: 4, 145-150.
 
4.
Bryson S.E.: Brief Report: Epidemiology of Autism. J Autism and Developmental Disorders 1996; 26: 165-167.
 
5.
Deisher T.A., Doan N.V., Omaiye A. et al: Impact of environmental factors on the prevalence of autistic disorder after 1979. J Public Health and Epidemiol 2014: 6(9): 271
 
6.
Fombonne E.: The epidemiology of autism: a review. Psychol Med 1999; 29(4): 769-786.
 
7.
Bittker S.: Infant Eksposure to Excessive Vitamin D: A Risk Factor for Autism Autism 2014; 4:1, 1-7.
 
8.
Gerhant A., Olajossy M., Olajossy-Hilkesberger L.: Neuroanatomiczne, genetyczne I neurochemiczne aspekty autyzmu dziecięcego. Psychiatr Pol 2013; 47(6): 1101-1111.
 
9.
Hertz-Picciotto G,. Croem L.A., Hansen R. et al: The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism. Environ Health Perspect 2006; 114: 1119-1125.
 
10.
Batley A., Le Carteur A., Gottesman I. et al: Autism as a strongly genetic disorder: evidence from a British twin study. Psychol Med 1995; 25(1): 63-77.
 
11.
Schendel D.E., Bresnahan M., Carter K.W. et al: The International Collaboration for Autism Registry Epidemiology (I CARE): Multinational Registry – Based Investigations of Autism Risk Factors and Trends. Autism Dev Disord 2013: 43: 2650-2663.
 
12.
Yeargin-Allsopp M.: Past and future perspectives in autism epidemiology. Molecular Psychiatry 2002; 7: S9-S11.
 
13.
Gerhant A., Olajossy M., Olajossy-Hilkesberger L.: Neuroanatomiczne, genetyczne I neurochemiczne aspekty autyzmu dziecięcego. Psychiatr Pol 2013; 47(6): 1101-1112.
 
14.
Nevison C.D.: A comparison of temporal trends in United States autism prevalence to trends in suspected environmental factors. Envir Health 2014; 13, 73: 1-16.
 
15.
Bryson S.E.: Brief Report: Epidemiology of Autism. J.Autism and Developmental Disorders 1996; 26, 2: 165-167.
 
16.
Wierzbiński P., Kwiatkowska A., Pietras T.: Neurorozwojowa teoria powstania autyzmu. Postępy Psych Neurol. 2003; 12(3): 347-355.
 
17.
Bettelheim B.: The empty fortress: Infantile autism and the birth of the self. 1972. New York: Free Press.
 
18.
Landrigan P.J., Lambertini L., Birnbaum L.S.: A research strategy to discover the environmental causes of autism and neurodevelopmental disabilities. Environ Health Perspect 2012; 120: 258-260.
 
19.
Landrigan J.P.: What causes autism? Exploring the environmental contribution. Current Opinion in Pediatrics 2010; 22: 219-255.
 
20.
Hass U., Lund S.P., Simonsen L. et al: Effects of prenatal exposure to xylene on postnatal development and behavior in rats. Neurotoxicol Teratol. 1995; 17(3): 341-349.
 
21.
Schetter T.: Developmental Disabilities – Impairment of Childrens Brain Development and Function: Te Role of Environmental Factors. Environm Health Perspectives 2001; Dec 109, Suppl 6: 813-816.
 
22.
Hurley A.M., Tadrous M., Miller E.: Thimerosal – Containing Vaccines and Autism: A Review of Recent Epidemiologic Studies. J Pediatr Pharmacol Ther 2010; 15: 173-181.
 
23.
Rutter M.: Incidence of autism spectrum disorders: changes over time and their meaning. Acta Paediatr 2005; 94: 2-15.
 
24.
Rodier P.M.: Początki autyzmu. Świat Nauki 2000, 5; 50- 57.
 
25.
Rodier P.M.: Converging evidence for brain stem injury in autism. Der Psychopathol. 2002; 14: 537-557.
 
26.
Snow W.M., Hartle K., Ivaco T.L.: Altered morphology of motor cortex neurons in the VPA rat model of autism. Der Psychobiol 2008; 50: 479-489.
 
27.
Rossignol D.A., Genuis S.J., Frey R.E.: Environmental toxicants and autism spectrum disorders: a systemic review. Transnational Psychiatry 2014; 4: 1-23.
 
28.
Levin E.D., Addy N., Nakojima A. et al: Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats brain. Res Dev Brain 2001; 130: 83-89.
 
29.
Szychowski K.A., Wojtowicz A.K.: Składniki tworzyw sztucznych zaburzające funkcje układu nerwowego. Postępy Hig Med. Dośw 2013; 67: 499-506.
 
30.
Hayek J. et al: Di-(2-etylhexal) phthalate and autism spectrum disorders. ASN Neuro 2012; 4: 223-229.
 
31.
Shelton J.F., Hertz-Picciotto J., Pessah I.N.: Tipping the Balance of Autism Risk: Potential Mechanisms linking Pesticides and Autism. Environ Health Perspect 2012; 120: 7; 944- 951. Pisula E.: Małe dziecko z autyzmem – diagnoza i terapia.
 
32.
Gdańskie Wydawnictwo Psychologiczne. Gdańsk 2005; ISBN 978-83-7489-298-8.
 
eISSN:2084-6312
ISSN:1505-7054
Journals System - logo
Scroll to top