During years 1991–2009 the blood samples from 175,000 children have been examined and the average blood lead level (Pb-B) gradual decrease over the years was observed. In 1991 the values of Pb-B were in range of 2.0–35 μg/dL with average of 10.12 μg/dL s44.47 μg/dL, in 2004 Pb-B was in range of 2.0–16.2 μg/dL and mean value 4.3 μg/dL s41.2 μg/dL, in 2006 Pb-B mean value was as low as 4.0 μg/dL s41.1 μg/dL and in 2009 Pb-B 4.1 μg/dL s41.1 μg/dL. The highest values of Pb-B were found in children living in the proximity of the copper smelting plants. The recent decrease of Pb-B in children to the values below 10 μg/dL Pb-B in comparison to levels found in the previous years is however still not satisfactory, since a very low Pb-B concentration even below 10 μg/dL may represent a risk factors for impairment of the central nervous functions, and as suggested in recent reviews, we also recommend that the acceptable level of Pb-B should be further reduced to below 2 μg/dL.