Introduction:
The Silesia Cancer Register conducts systematic monitoring of the cancer incidence since 60-years XX c. within Silesia voivodeship. The Register encompasses the area that is inhabited about 4.8 mln inhabitants, according to the Main Bureau of Statistics. Amount of the persons suffering for cancer constantly increasing, although unequally by smaller administrative units, i.e 36 districts. Therefore necessity looking for really endemic area, especially with the biggest and smallest cancer incidence rates.

Material and Methods:
Using the M. Segi’s and M. Kurihara’s procedure in the R. Doll’s modification the average incidence rates (partial, crude and standardized by the “age-world population structure”) – were calculated. The analysis was based on the 183.396 cases of persons (males, females) that were suffered on this area in the years 1999–2009.

Results:
In the year 1999–2009 in Silesia Voivodeship, 94.001 cases of all cancer (i.e 51.3 % from total) were diagnosed among males, and 89.395 cases (i.e 48.7%) among females. Age-adjusted incidence rates varied from minimum 227.0 to maximum 327.0/100 thousand (average for whole areas – 272.4/100 thousand) among males and females. The distribution of age-standardized cancer incidence rates (in periods: 1999–2009, 1999–2002 and 2006– 2009) for all sites by both sexes is very unequal. The rates of incidence were used in the chorological type of analyses (a looking for of endemic areas especially with the biggest incidence). There endemic areas were described (vide fig 1D and 2D). The most frequent and long-lasting suffering males and females in the following counties: będziński, bielski, cieszyński, mikołowski and towns: Bielsko-Biała, Chorzów, Dąbrowa Górnicza, Gliwice, Jaworzno, Jastrzębie-Zdrój, Katowice, Tychy, Żory.

Conclusions:
This analysis is a based to organize of diverse mainly prevention activities, i.e anti-cancer education, screenings, etc.